Obstetric And Perinatal Outcomes In Singleton Pregnancies Resulting From IVF/ICSI; A Systematic Review
Published 2025-11-10
Keywords
- Outcomes, Complications, IVF/ICSI, Singleton pregnancy.
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Abstract
Background: Assisted reproductive technology is implemented to help infertile couples to achieve pregnancy. It involves in vitro fertilization and intracytoplasmic sperm injection. This technology has been increasingly used; however, several complications have been found to be associated with the technology. Recent systematic analysis of previous literature is lacking.
Aim: To assess the outcomes of singleton pregnancies following IVF/ICSI by reviewing the previous studies assessed this subject.
Methods: The databases of PubMed, Springer, Elsevier, Science Direct, and Google Scholar were explored for articles concerned with the current subject that were published after 2012. The search terms, including "IVF, ICSI, IVF/ICSI, Outcomes, Adverse Outcomes, Complications, Perinatal, Obstetric, Gestational, Pregnancy, Maternal, Neonatal, and Outcomes," were used for the search process. English Original articles focused on our subject and available for full text were included in this review.
Results: There were eight studies that fulfilled the inclusion criteria and were involved in this review. The included studies involved 335881 women with ages ranging from 18 to 48 years.
Conclusion: Singleton pregnancies after IVF/ICSI were associated with various obstetric and perinatal adverse outcomes for both the mother and her neonates compared to those who conceive spontaneously.