For health sciences, it's important to understand the factors that influence health-related behaviors. This information is key to creating personalized and effective interventions. Caregivers of people with disabilities often have a hard time taking care of themselves because of the emotional, social, and cultural challenges that come with their role. Interventions for this group must be based on theory to understand the cognitive, emotional, and social processes involved in behavior change. This essay looks at five important models: the Theory of Reasoned Action, the Transtheoretical Model of Health Behavior, the Motivational Interviewing Model, the Theory of Self-Efficacy, and the Health Promotion Model proposed by Nola Pender. The goal is to combine these models in a way that can be used in the future to support interventions with informal caregivers. The analysis shows how each model helps us understand the caregiver context. The Theory of Reasoned Action shows how people's beliefs about what others think can influence their actions. It often makes people think that taking care of themselves is a selfish act, which can lead to more people neglecting themselves. The Transtheoretical Model is a way of thinking about change that is continuous and nonlinear. This means that it can be used to create programs that are designed to fit the specific stage of readiness of the caregiver. The Motivational Interviewing and Self-Efficacy Models emphasize that internal drives and the belief in one's ability (self-efficacy) are key factors in determining whether someone will take action and keep up a new behavior. Nola Pender's model combines these ideas, emphasizing the impact of past experiences, personal characteristics, and perceived advantages or challenges. The idea behind this is that changes in how informal caregivers act are affected by what they believe and what they think they can do, as well as by what other people expect of them and the world around them. Therefore, effective interventions must be personalized to address the caregiver's self-efficacy, cultural beliefs, and stage of change. This will facilitate a shift from feeling a moral obligation to caring for someone to sustainable self-care.