Occupational stress-related burnout is a significant challenge in the healthcare sector; it not only affects the welfare of the healthcare workforce but also the quality of healthcare service. This article explains the main causes, symptoms, and consequences of burnout among healthcare workers, highlighting the major roles of occupational pressures, emotional exhaustion, and organizational issues in burnout. The other main consequences for the employee—physiological, psychological, and social—include loss of productivity, job satisfaction, and mental health issues, among others. The article also discusses remedies and strategies to mitigate burnout, including organizational reforms, resilience training, and peer support programs. The findings emphasize the need to address the root causes of burnout and the necessity for comprehensive workplace interventions to promote healthcare workers' mental health. Recommendations for the prevention and alleviation of burnout include improving work-life balance, increasing organizational support, and creating a friendly workplace environment. It also gives important lessons to be learned for healthcare managers and governmental bodies looking for better staff health and better patient outcomes.