Background: Nursing interventions play a critical role in shaping patient safety, satisfaction, and clinical outcomes across healthcare systems. As frontline providers, nurses influence care quality through direct clinical actions, preventive practices, patient education, and care coordination. Despite extensive research, evidence on the collective impact of nursing interventions remains dispersed across specialties and settings.

Aim: This integrative review aims to synthesize existing evidence on the impact of nursing interventions on patient safety, patient satisfaction, and clinical outcomes across diverse healthcare contexts.

Methods: An integrative review methodology was employed to analyze peer-reviewed studies published in recent years. Major healthcare databases were searched, and eligible studies were systematically screened and thematically analyzed to identify key categories of nursing interventions and outcome domains.

Results: Findings indicate that nursing interventions are consistently associated with reductions in adverse events, improvements in patient satisfaction and experience, and enhanced clinical outcomes such as reduced length of stay, lower complication rates, and improved recovery trajectories. The effectiveness of these interventions is further influenced by workforce capacity, education, leadership support, and organizational context.

Conclusion: Nursing interventions represent a foundational determinant of healthcare quality and patient outcomes. Strengthening evidence-based nursing practices and supportive systems is essential for advancing patient-centered, safe, and effective healthcare delivery.