Diabetes mellitus represents a growing global public health challenge with profound clinical, social, and economic consequences. Its prevention and long-term management extend beyond medical treatment to encompass health awareness, community culture, and the capacity of healthcare systems to deliver continuous and secure care. This article explores the interrelated roles of nursing, health information systems, and health security in diabetes prevention and in improving quality of life, within the broader context of community culture and health awareness.

The review highlights that inadequate health literacy and culturally incongruent health interventions remain major barriers to effective diabetes prevention and self-management. Nursing professionals play a pivotal role in addressing these gaps through health education, early screening, psychosocial support, and culturally sensitive patient engagement. In parallel, health information systems enhance diabetes care by supporting early risk identification, continuity of care, data-driven decision-making, and patient empowerment through access to reliable health information. Health security frameworks further underpin these efforts by ensuring the continuity of essential services, protection of healthcare facilities and data, and resilience of diabetes care during public health emergencies.

The findings underscore that sustainable diabetes prevention and improved quality of life are best achieved through integrated approaches that align nursing practice, robust health information systems, and health security within the cultural realities of communities. Strengthening these interconnected domains is essential for reducing diabetes-related complications, enhancing patient engagement, and mitigating the long-term burden of diabetes on individuals and healthcare systems.