The healthcare landscape in Saudi Arabia is undergoing a profound transformation as part of Vision 2030, with a strategic emphasis on integrated care delivery systems that prioritize patient-centered approaches. This study examines the synergistic roles of key healthcare professionals—physicians, nurses, radiology technicians, and healthcare administrators—within Saudi Arabia's evolving healthcare ecosystem. Through a comprehensive analysis of recent literature and empirical studies, this paper explores the collaborative dynamics, challenges, and opportunities that characterize interprofessional practice in Saudi healthcare institutions. Particular attention is given to how these professional groups interact to deliver coordinated care, the systemic barriers they face, and emerging models that promote effective collaboration. The findings suggest that while significant progress has been made in fostering interprofessional collaboration, persistent structural, educational, and cultural challenges require targeted interventions. The article concludes with evidence-based recommendations for strengthening collaborative practice frameworks, enhancing interprofessional education, and developing leadership approaches that support integrated care delivery in the unique sociocultural context of Saudi Arabia.