Cultura

Scientific Perspectives Of Evolutionary Theory And Integrated Science Education

VOLUME 23, 2026

The Role of Targeted Infra-popliteal Endovascular Angioplasty to Treat Diabetic Foot Ulcers Using the Angiosome Model: A Systematic Review

VOLUME 6, 2023

Jun-young Oh, Yumi Lee, Khujanazarov Uktam Eshtemirovich, Khujanov Erkin

Abstract

It can be said that current science education and liberal arts education do not present the concept of biological evolution as a core concept that integrates the entire concept of life science. Therefore, the purpose of this study is to explore the convergence of science and the humanities, and above all, the integration between sciences, through a biological lens. Through this theory of biological evolution, the possibility of convergence between different disciplines is explored. It can be seen as meaning an essentialist and reductionist integration centered on physics. However, it demands integration from an evolutionary standpoint that speaks of change and creation.

Methodologically, the cosmological goal of stability and the evolutionary product of the human mind, cooperation, should be integrated with the natural sciences as the main goal. That is, the biological evolutionary mechanism (Base Domain) should be extended to other academic fields (Target Domain). A powerful methodology is the analogical strategy.

Reductionist approaches to physics and chemistry and biology are essentially different. The theory of evolution combines biology as well as other disciplines to form a so-called consilience of knowledge. At its core, it can be said that natural selection is based on moral cooperation (civilization) rather than biological competition (elimination).

Through these studies, we argue that interdisciplinary convergence and connection should be made based on the philosophical characteristics of the theory of biological evolution, which requires generation and change. It can be said that integrated science, which is made up of connections between current disciplines, is simply an integration that can be connected academically according to the theory of reductionist classical physics. It is argued that integrated education should be made based on the change and diversity contained in the theory of biological evolution in the current integrated science textbooks. Because, beyond the fixed and unchanging essentialist metaphysics of physics and chemistry, Dewey's philosophical view of change, creation and change, a constructivist world view, biological evolution theory should be attempted to converge.

Keywords : mechanical materialism, quantitative change, immutability, creation of change, evolutionary theory, integration, moral cooperation.
Erin Saricilar
Lecture in accounting. University of Basrah, College of Administration and Economics, Department of Accounting.

Abstract

Atherosclerotic disease significantly impacts patients with type 2 diabetes, who often present with recalcitrant peripheral ulcers. The angiosome model of the foot presents an opportunity to perform direct angiosome-targeted endovascular interventions to maximise both wound healing and limb salvage. A systematic review was performed, with 17 studies included in the final review. Below-the-knee endovascular interventions present significant technical challenges, with technical success depending on the length of lesion being treated and the number of angiosomes that require treatment. Wound healing was significantly improved with direct angiosome-targeted angioplasty, as was limb salvage, with a significant increase in survival without major amputation. Indirect angioplasty, where the intervention is applied to collateral vessels to the angiosomes, yielded similar results to direct angiosome-targeted angioplasty. Applying the angiosome model of the foot in direct angiosome-targeted angioplasty improves outcomes for patients with recalcitrant diabetic foot ulcers in terms of primary wound healing, mean time for complete wound healing and major amputation-free survival.
Keywords : Diabetic foot ulcer, angiosome, angioplasty