Cultura

Autism Spectrum Disorder And Significant Behavioral Changes

VOLUME 22, 2025

The Role of Targeted Infra-popliteal Endovascular Angioplasty to Treat Diabetic Foot Ulcers Using the Angiosome Model: A Systematic Review

VOLUME 6, 2023

Najya Abdullah Attia, Fares Abed Althobaiti, Abdulaziz abdullah Sharkar, Abdullah Essa AlEssa, Saud Ahmed Almudarra, Hoda Jehad Abousada, Ola Latif Abumansour, Ahlam Abdulkarim Aldarwish
Sarah Ismail Marzouk, Lama Saad Alghamdi, Fatimah Hassan Alshihabi, Fatema Jehad BinRajab, Bayan Ghassan Fatta, Reema Mohammed Alshehri, Fada Naji Al nihab

Abstract

Objective: In order to determine common triggers or correlated causes of behavioral changes (e.g., puberty, environment, co-morbidities, therapeutic interventions), the study's primary goal is to investigate the type and degree of significant behavioral changes among people with autism spectrum disorder. Additionally, the study will evaluate how well the present methods of behavior management used by professionals and caregivers are working.

Methods: This study will use a cross-sectional descriptive approach to evaluate the noteworthy behavioral alterations seen in people with autism spectrum disorder (ASD) and the factors that contribute to those alterations. In the Kingdom of Saudi Arabia, the cross-sectional approach allows the researcher to gather information from a large number of participants at one time, giving a glimpse of the patterns and degree of behavioral differences among people with ASD across different age groups, severity levels, and sociocultural contexts.

Results: The study included 450 participants. The most frequent Child’s Age among them was 3-5 years old (n=167, 37.1%), followed by 6-10 years old (n=156, 34.7%), then 0-2 years old (n=99, 22%), at least 11-16 years old (n=28, 6.2%). The most frequent Child gender among study participants was male (n=237, 52.7 %) and female (n=213, 47.3%). The most frequent child with autism spectrum disorder among study participants was No (n=401, 89.1%), followed by Yes (n=49, 10.9%). Educational level of parents of children with autism spectrum disorder (ASD) among study participants, the majority were Postgraduate (n=31, 63.3%), followed by Secondary (n=13, 26.5%), then Primary (n=5, 10.2%). Employment Status of parents of children with autism spectrum disorder (ASD) among study participants, most of them were Employed Full-Time (n=34, 69.4%), followed by Housewife (n=8, 16.3%), then Part-Time (n=4, 8.2%), and at least Unemployed (n=8, 16.3%). The participants were asked how the child was diagnosed with ASD, most of them answered Pediatrician (n=21, 42.9%), followed by Psychologist (n=14, 28.6%), then Neurologist (n=3, 6.1%). Participants were asked Did cultural or social stigma delay seeking medical help, most of them answered no (n=34, 69.4%), followed by not sure (n=10, 20.4%), then yes (n=5, 10.2%). Participants were asked Do you feel stress in managing your child’s behavior. The most frequent were occasionally (n=24, 49%), followed by rarely (n=13, 26.5%), then frequently (n=9, 18.4%), and never (n=3, 6.1%). Participants were asked, about Does your child attend a special education center/school. The most frequent were yes (n=26, 53.1%), then no (n=18, 36.7%), and planning to enroll (n=5, 10.2%). Participants were asked Has your child shown behavioral improvement with therapy; Most reported Significant improvement (n=19, 38.8%), followed by Moderate improvement (n=16, 32.7%), then no noticeable change (n=14, 28.6%).

Conclusion: The results showed significant associations between children's behavioral outcomes and several factors, including age, age at diagnosis, parental education, employment status, and method of diagnosis. These findings indicate that demographic and diagnostic characteristics influence behavioral patterns in children with ASD. In contrast, no significant relationship was found with gender.

Keywords : .
Erin Saricilar
Lecture in accounting. University of Basrah, College of Administration and Economics, Department of Accounting.

Abstract

Atherosclerotic disease significantly impacts patients with type 2 diabetes, who often present with recalcitrant peripheral ulcers. The angiosome model of the foot presents an opportunity to perform direct angiosome-targeted endovascular interventions to maximise both wound healing and limb salvage. A systematic review was performed, with 17 studies included in the final review. Below-the-knee endovascular interventions present significant technical challenges, with technical success depending on the length of lesion being treated and the number of angiosomes that require treatment. Wound healing was significantly improved with direct angiosome-targeted angioplasty, as was limb salvage, with a significant increase in survival without major amputation. Indirect angioplasty, where the intervention is applied to collateral vessels to the angiosomes, yielded similar results to direct angiosome-targeted angioplasty. Applying the angiosome model of the foot in direct angiosome-targeted angioplasty improves outcomes for patients with recalcitrant diabetic foot ulcers in terms of primary wound healing, mean time for complete wound healing and major amputation-free survival.
Keywords : Diabetic foot ulcer, angiosome, angioplasty