Cultura

Obstetric And Perinatal Outcomes In Singleton Pregnancies Resulting From IVF/ICSI; A Systematic Review

VOLUME 22, 2025

The Role of Targeted Infra-popliteal Endovascular Angioplasty to Treat Diabetic Foot Ulcers Using the Angiosome Model: A Systematic Review

VOLUME 6, 2023

Malak Qasem Alalwan, Roaa Abdullah Buhligah, Gofran Mohammed Al-braheem, Amjad Wahab Alquraini, Wejdan Hussain Alomran, Rehab Abdulmajid Albinessa, Maryam Fahad AlJuwaysim, Layla Anwar lmarzooq, Marwah Abdulaziz Alhadi

Abstract

Background: Assisted reproductive technology is implemented to help infertile couples to achieve pregnancy. It involves in vitro fertilization and intracytoplasmic sperm injection. This technology has been increasingly used; however, several complications have been found to be associated with the technology. Recent systematic analysis of previous literature is lacking.

Aim: To assess the outcomes of singleton pregnancies following IVF/ICSI by reviewing the previous studies assessed this subject.

Methods: The databases of PubMed, Springer, Elsevier, Science Direct, and Google Scholar were explored for articles concerned with the current subject that were published after 2012. The search terms, including "IVF, ICSI, IVF/ICSI, Outcomes, Adverse Outcomes, Complications, Perinatal, Obstetric, Gestational, Pregnancy, Maternal, Neonatal, and Outcomes," were used for the search process. English Original articles focused on our subject and available for full text were included in this review. 

Results: There were eight studies that fulfilled the inclusion criteria and were involved in this review. The included studies involved 335881 women with ages ranging from 18 to 48 years.

Conclusion: Singleton pregnancies after IVF/ICSI were associated with various obstetric and perinatal adverse outcomes for both the mother and her neonates compared to those who conceive spontaneously.

Keywords : Outcomes, Complications, IVF/ICSI, Singleton pregnancy..
Erin Saricilar
Lecture in accounting. University of Basrah, College of Administration and Economics, Department of Accounting.

Abstract

Atherosclerotic disease significantly impacts patients with type 2 diabetes, who often present with recalcitrant peripheral ulcers. The angiosome model of the foot presents an opportunity to perform direct angiosome-targeted endovascular interventions to maximise both wound healing and limb salvage. A systematic review was performed, with 17 studies included in the final review. Below-the-knee endovascular interventions present significant technical challenges, with technical success depending on the length of lesion being treated and the number of angiosomes that require treatment. Wound healing was significantly improved with direct angiosome-targeted angioplasty, as was limb salvage, with a significant increase in survival without major amputation. Indirect angioplasty, where the intervention is applied to collateral vessels to the angiosomes, yielded similar results to direct angiosome-targeted angioplasty. Applying the angiosome model of the foot in direct angiosome-targeted angioplasty improves outcomes for patients with recalcitrant diabetic foot ulcers in terms of primary wound healing, mean time for complete wound healing and major amputation-free survival.
Keywords : Diabetic foot ulcer, angiosome, angioplasty