Bioethical Philosophical Dialogue under the Hegemony of Scientific Progress
VOLUME 23, 2026
The Role of Targeted Infra-popliteal Endovascular Angioplasty to Treat Diabetic Foot Ulcers Using the Angiosome Model: A Systematic Review
VOLUME 6, 2023
Boughoufala Ahmed, Derras Shahrazed, Belakhdar Wahid, Mahmoudi Khelifa
Abstract
Bioethics is considered one of the new fields of knowledge concerning ethical issues arising from the outcomes of biological and medical research involving human beings. It does so by establishing a set of moral values intended to guide the work and research of physicians and scientists and by determining their ethical parameters to preserve human life and dignity. This has led philosophers to direct their attention toward bioethics, regarding it as a fundamental point of reference for discussing and raising their questions through the diagnosis of lived reality and its treatment from a critical perspective. Such a perspective seeks to establish a new space for philosophising, aiming to understand, interpret, and analyse the reality of human life. This, in turn, has given rise to a bioethical philosophical dialogue that examines the transgressions imposed by scientific progress and seeks to establish new ethics specific to the sciences. These ethics contribute to the continuation of philosophical discourse concerning the legitimacy of science and represent the future of philosophical inquiry in the ethical domain.
Keywords :
Bioethics; philosophy; scientific progress; ethics of science; medicine; biology; ethics..
Erin Saricilar
Lecture in accounting. University of Basrah, College of Administration and Economics, Department of Accounting.
Lecture in accounting. University of Basrah, College of Administration and Economics, Department of Accounting.
Abstract
Atherosclerotic disease significantly impacts patients with type 2 diabetes, who often present with recalcitrant peripheral ulcers. The angiosome model of the foot presents an opportunity to perform direct angiosome-targeted endovascular interventions to maximise both wound healing and limb salvage. A systematic review was performed, with 17 studies included in the final review. Below-the-knee endovascular interventions present significant technical challenges, with technical success depending on the length of lesion being treated and the number of angiosomes that require treatment. Wound healing was significantly improved with direct angiosome-targeted angioplasty, as was limb salvage, with a significant increase in survival without major amputation. Indirect angioplasty, where the intervention is applied to collateral vessels to the angiosomes, yielded similar results to direct angiosome-targeted angioplasty. Applying the angiosome model of the foot in direct angiosome-targeted angioplasty improves outcomes for patients with recalcitrant diabetic foot ulcers in terms of primary wound healing, mean time for complete wound healing and major amputation-free survival.
Keywords :
Diabetic foot ulcer, angiosome, angioplasty