Marxism believes that literary and artistic creation is a special kind of spiritual production activity of human beings, and only those who are engaged in literary and artistic production activities and have subjectivity and self-consciousness are the real subjects of literary and artistic creation. Along with the progress of artificial intelligence, the development of cross-border fusion of art and science and technology has entered a brand-new period, promoting the continuous development of contemporary art in the direction of diversification, digitization, and cross-media. In the face of the changes brought by AI to the contemporary art landscape in the fields of semantic reconstruction, paradigm shift, and industrial reshaping, relevant theoretical research on the fusion of art science and technology is also underway. The paper aims to explore the impact and reflections of Artificial Intelligence (AI) on artistic creation within the framework of the Marxist conception of artistic production. The Marxist Theory of socio-historical materialism provides a powerful tool to analyze how art reflects social structures and class forces. As a product of modern technology and its application in art, AI has triggered new thinking about creative labor, cultural industries, and the nature of the class.